Virtual Reality and Pre-Operative Anxiety: How to Eliminate Fear Before Surgery

Virtual Reality and Pre-Operative Anxiety: How to Eliminate Fear Before Surgery

The most difficult moment for a surgical patient is often not the surgery itself. It is the waiting. The holding area, the gurney, the gown. The anxiety building up while waiting for one's turn.

The problem: preoperative anxiety is the norm, not the exception

Between 60% and 80% of patients experience clinically significant anxiety before elective surgery. This is not irrational fear: it is a normal physiological response to a perceived threatening situation.

The consequences are concrete and measurable for the department:

  • Increased consumption of anesthetic agents (anxious patients require higher doses)

  • Slower postoperative recovery in patients presenting with high cortisol levels

  • Higher incidence of postoperative nausea and vomiting

  • On average longer hospital stays

  • Negative patient experience ratings even in cases of excellent clinical outcomes

Standard pharmacological treatment — preoperative benzodiazepines or other anxiolytics — resolves anxiety but adds anesthesiological complexity, prolonged recovery, and risks of drug interactions. Many anesthesiologists would prefer to avoid using it when possible.

How VR works in the holding area

Immersive virtual reality therapy intervenes during the most critical phase: the 15-30 minutes of waiting before surgery. The patient wears a VR headset and is immersed in a relaxing natural environment — a beach, a forest, a mountain landscape — with binaural audio that stimulates the parasympathetic nervous system.

The mechanism is not simple distraction. Immersive VR activates the autonomic relaxation response: it reduces heart rate, lowers salivary cortisol, and alters amygdala activation. The patient arrives in the operating room in a significantly different physiological state.

What the research says

Evidences of VR for preoperative anxiety are today among the most robust in clinical literature:

  • JMIR Meta-analysis (2025) on 18 RCTs: 28% reduction in preoperative anxiety compared to placebo, statistically significant in 16 out of 18 studies

  • Hospital Clínic Barcelona study (2024): Preoperative VR equivalent to benzodiazepines in reducing anxiety in cancer patients, without pharmacological side effects

  • RCT on elective gynecoperating surgery (Springer 2025): 18% reduction in time to reach sedation in patients who had received preoperative VR

  • Policlinico Gemelli review (2026): VR protocol in the pre-anesthesia room — 31% reduction in anxiety and +22 NPS points improvement in patient experience ratings

The practical protocol: under 2 minutes of setup

  1. Reception (30 seconds): the nurse informs the patient about the VR option. It is not mandatory. Spontaneous compliance in departments that have adopted it exceeds 80%.

  2. Setup (45 seconds): the headset is placed on the patient already on the preoperative gurney. It requires neither a sitting position nor active cooperation.

  3. Immersion (15-30 minutes): the patient remains immersed for the duration of the wait. Staff can continue their activities normally.

  4. Removal (10 seconds): the headset is removed before entering the operating room. The patient is present and cooperative.

The headset remains accessible along the patient's arm and neck during the entire preparatory phase. It does not interfere with the IV cannula, blood pressure cuff, or ECG electrodes.

For which departments is it most indicated

Preoperative anxiety is a cross-cutting issue, but some contexts show particularly marked benefits:

  • Oncological surgery: patients already arrive with high anxiety levels related to the diagnosis. Preoperative VR is among the interventions with the greatest measurable impact.

  • Day surgery: patients do not have time to adjust to the hospital environment. Anxiety is concentrated in the few minutes before surgery.

  • Pediatric surgery: in children, preoperative anxiety manifests more intensely and has more marked effects on postoperative recovery.

  • Procedures under local anesthesia or sedation: the patient is conscious during the procedure and anxiety control becomes an integral part of the anesthetic protocol.

The value for the department

Beyond the direct benefit to the patient, reducing preoperative anxiety produces measurable clinical and operational advantages. Departments adopting preoperative VR protocols consistently report reduced use of pre-anesthetic sedative medications, faster induction times, and higher patient experience ratings.

Immersive therapy in this context is not an optional comfort. It is a level I evidence-based clinical intervention that improves both surgical outcomes and patient experience simultaneously.

Conclusion

Preoperative anxiety is manageable. There is no need to add drugs to the anesthesia chart — all that is needed is a headset, 45 seconds of setup, and a patient arriving in the operating room in an optimal physiological state. The evidence is there. The protocol is proven. The question is not whether it works, but when to start.